TMEM120B Gene Summary [Human]
Predicted to be involved in fat cell differentiation and protein heterooligomerization. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | TMEM120B |
| Official Name | transmembrane protein 120B [Source:HGNC Symbol;Acc:HGNC:32008] |
| Ensembl ID | ENSG00000188735 |
| Bio databases IDs | |
| Aliases | transmembrane protein 120B |
| Synonyms | LOC100133827, LOC687611, transmembrane protein 120B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM120B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- TMPIT-like protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- inner nuclear membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM120B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein heterooligomerization
- fat cell differentiation
Cellular Component
Where in the cell the gene product is active
- nuclear inner membrane
Molecular Function
What the gene product does at the molecular level
- ion channel activity
- protein binding