REEP4 Gene Summary [Human]
Predicted to enable microtubule binding activity. Involved in mitotic nuclear membrane reassembly. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | REEP4 |
| Official Name | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] |
| Ensembl ID | ENSG00000168476 |
| Bio databases IDs | |
| Aliases | receptor accessory protein 4 |
| Synonyms | 2700029E10Rik, C8orf20, PP432, receptor accessory protein 4, RGD1306561, Yip2c |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human REEP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- TB2/DP1, HVA22 family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human REEP4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- mitotic nuclear envelope reassembly
- nuclear envelope organization
- endoplasmic reticulum tubular network organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum tubular network
- endoplasmic reticulum
- cytoplasmic microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding