ZAR1L Gene Summary [Human]

This gene encodes a member of the ZAR1 family that is predominantly expressed in oocytes and early embryos. The protein may function as an RNA regulator in early embryos. [provided by RefSeq, Apr 2010]

Details

Type
Protein Coding
Official Symbol
ZAR1L
Official Name
zygote arrest 1 like [Source:HGNC Symbol;Acc:HGNC:37116]
Ensembl ID
ENSG00000189167
Bio databases IDs NCBI: 646799 Ensembl: ENSG00000189167
Aliases zygote arrest 1 like, zinc finger, 3CxxC-type 7
Synonyms AABR07034923.1, LOC682680, XM 359419, Z3CXXC7, ZAR2, zygote arrest 1-like
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZAR1L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • mRNA 3' UTR binding
  • Zinc-binding domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic kidney disease
regulated by
role in cell
  • translation in
  • maturation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • organelle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZAR1L gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • oocyte maturation
  • negative regulation of translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • intracellular non-membrane-bounded organelle

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • mRNA 3'-UTR binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.