KIF19 Gene Summary [Human]
Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in axonemal microtubule depolymerization; microtubule-based movement; and plus-end specific microtubule depolymerization. Predicted to be located in cilium. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | KIF19 |
| Official Name | kinesin family member 19 [Source:HGNC Symbol;Acc:HGNC:26735] |
| Ensembl ID | ENSG00000196169 |
| Bio databases IDs | |
| Aliases | kinesin family member 19 |
| Synonyms | KIF19A, kinesin family member 19, kinesin family member 19A, RGD1559936 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KIF19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinesin motor, catalytic domain
- Myosin and Kinesin motor domain
- Kinesin motor domain
- plus-end-directed kinesin ATPase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KIF19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- plus-end specific microtubule depolymerization
- axonemal microtubule depolymerization
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- cilium
- kinesin complex
- axoneme
- microtubule
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- plus-end-directed microtubule motor activity
- microtubule binding