POTEF Gene Summary [Human]

Involved in retina homeostasis. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
POTEF
Official Name
POTE ankyrin domain family member F [Source:HGNC Symbol;Acc:HGNC:33905]
Ensembl ID
ENSG00000196604
Bio databases IDs NCBI: 728378 Ensembl: ENSG00000196604
Aliases POTE ankyrin domain family member F
Synonyms A26C1B, ACTB, POTE2alpha, POTEACTIN, POTE ankyrin domain family member F, POTE ankyrin domain family, member F
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human POTEF often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ankyrin repeats (many copies)
  • Actin
  • Ankyrin repeats (3 copies)
  • protein binding
  • Ankyrin repeat
  • ASKHA_ATPase-like
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human POTEF gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell motility
  • axonogenesis

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular vesicular exosome
  • NuA4 histone acetyltransferase complex
  • cytoplasm
  • cell cortex
  • blood microparticle
  • membrane
  • actin cytoskeleton
  • synapse
  • actin filament
  • axon

Molecular Function

What the gene product does at the molecular level
  • protein kinase binding

Gene-Specific Assays for Results You Can Trust

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