WDR5B Gene Summary [Human]

This intronless gene encodes a protein containing several WD40 repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, including a trp-asp at the C-terminal end. The encoded protein may mediate protein-protein interactions. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
WDR5B
Official Name
WD repeat domain 5B [Source:HGNC Symbol;Acc:HGNC:17826]
Ensembl ID
ENSG00000196981
Bio databases IDs NCBI: 54554 Ensembl: ENSG00000196981
Aliases WD repeat domain 5B
Synonyms 2310009C03Rik, WD repeat domain 5B
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WDR5B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • WD40
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
regulated by
  • ammonium

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human WDR5B gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • Set1C/COMPASS complex

Molecular Function

What the gene product does at the molecular level
  • histone binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.