EIF1AY Gene Summary [Human]

This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Details

Type
Protein Coding
Official Symbol
EIF1AY
Official Name
eukaryotic translation initiation factor 1A Y-linked [Source:HGNC Symbol;Acc:HGNC:3252]
Ensembl ID
ENSG00000198692
Bio databases IDs NCBI: 9086 Ensembl: ENSG00000198692
Aliases eukaryotic translation initiation factor 1A Y-linked
Synonyms eIF-4C, eukaryotic translation initiation factor 1A Y-linked
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EIF1AY often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • S1_like
  • Translation initiation factor 1A / IF-1
  • protein binding
  • translation regulator

Pathways

Biological processes and signaling networks where the EIF1AY gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic inflammatory myopathy
  • autism
  • severe acute respiratory syndrome
  • systemic lupus erythematosus
role in cell
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human EIF1AY gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • translational initiation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • translation initiation factor activity
  • protein binding
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.