GPANK1 Gene Summary [Human]
This gene is located in a cluster of HLA-B-associated transcripts, which is included in the human major histocompatability complex III region. This gene encodes a protein which is thought to play a role in immunity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2010]
Details
| Type | Protein Coding |
| Official Symbol | GPANK1 |
| Official Name | G-patch domain and ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:13920] |
| Ensembl ID | ENSG00000204438 |
| Bio databases IDs | |
| Aliases | G-patch domain and ankyrin repeats 1, G patch domain containing 10, ankyrin repeat domain 59 |
| Synonyms | ANKRD59, BAT4, D17H6S54E, D6S54E, G5, GPATCH10, G-patch domain and ankyrin repeats 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPANK1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- G-patch domain
- Ankyrin repeats (3 copies)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPANK1 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- protein binding