REPIN1 Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of glucose import and regulation of fatty acid transport. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | REPIN1 |
| Official Name | replication initiator 1 [Source:HGNC Symbol;Acc:HGNC:17922] |
| Ensembl ID | ENSG00000214022 |
| Bio databases IDs | |
| Aliases | replication initiator 1, replication initiation region protein (60kD), zinc finger protein AP4, zinc finger protein 464 (RIP60) |
| Synonyms | AP4, E430037F08Rik, MGC19105, replication initiator 1, RIP60, Zfp-464, ZNF464 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human REPIN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- Zinc-finger double domain
- protein binding
- sequence-specific DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- ribosome
- lipid droplets
- cytosol
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human REPIN1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of fatty acid transport
- DNA replication
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- cytosol
- chromosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- metal ion binding
- chromatin insulator sequence binding
- sequence-specific DNA binding