Repin1 Gene Summary [Mouse]
Predicted to enable chromatin insulator sequence binding activity and sequence-specific DNA binding activity. Involved in regulation of fatty acid transport and regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of D-glucose import. Located in cytosolic ribosome; lipid droplet; and nuclear membrane. Is expressed in central nervous system and genitourinary system. Orthologous to human REPIN1 (replication initiator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Repin1 |
| Official Name | replication initiator 1 [Source:MGI Symbol;Acc:MGI:1889817] |
| Ensembl ID | ENSMUSG00000052751 |
| Bio databases IDs | |
| Aliases | replication initiator 1 |
| Synonyms | AP4, E430037F08Rik, MGC19105, replication initiator 1, RIP60, Zfp-464, ZNF464 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Repin1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- Zinc-finger double domain
- protein binding
- sequence-specific DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- ribosome
- lipid droplets
- cytosol
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Repin1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of fatty acid transport
- DNA replication
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- cytosol
- chromosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- metal ion binding
- chromatin insulator sequence binding
- sequence-specific DNA binding