NPS Gene Summary [Human]
Predicted to be involved in positive regulation of GABAergic synaptic transmission; positive regulation of action potential; and positive regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within visual learning. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NPS |
| Official Name | neuropeptide S [Source:HGNC Symbol;Acc:HGNC:33940] |
| Ensembl ID | ENSG00000214285 |
| Bio databases IDs | |
| Aliases | neuropeptide S, prepro-neuropeptide S |
| Synonyms | neuropeptide S, NPS precursor |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NPS often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neuropeptide S precursor protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NPS gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- positive regulation of action potential
- positive regulation of synaptic transmission, GABAergic
- positive regulation of circadian sleep/wake cycle, wakefulness
- visual learning
- positive regulation of synaptic transmission, glutamatergic
- synaptic transmission, glutamatergic
Cellular Component
Where in the cell the gene product is active
- synapse
- extracellular region