Nps Gene Summary [Rat]
Involved in positive regulation of circadian sleep/wake cycle, wakefulness. Predicted to be located in extracellular region and synapse. Used to study morphine dependence. Orthologous to human NPS (neuropeptide S). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nps |
| Official Name | neuropeptide S [Source:RGD Symbol;Acc:2324597] |
| Ensembl ID | ENSRNOG00000036653 |
| Bio databases IDs | |
| Aliases | neuropeptide S |
| Synonyms | neuropeptide S, NPS precursor |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nps often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neuropeptide S precursor protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nps gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- positive regulation of action potential
- positive regulation of synaptic transmission, GABAergic
- positive regulation of circadian sleep/wake cycle, wakefulness
- visual learning
- positive regulation of synaptic transmission, glutamatergic
- synaptic transmission, glutamatergic
Cellular Component
Where in the cell the gene product is active
- synapse
- extracellular region