AS3MT Gene Summary [Human]
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | AS3MT |
| Official Name | arsenite methyltransferase [Source:HGNC Symbol;Acc:HGNC:17452] |
| Ensembl ID | ENSG00000214435 |
| Bio databases IDs | |
| Aliases | arsenite methyltransferase |
| Synonyms | 2310045H08Rik, arsenite methyltransferase, CYT19 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AS3MT often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein methyltransferase
- enzyme
- AdoMet_MTases
- methyltransferase domain
- S-adenosylmethionine-dependent methyltransferase
- arsenite methyltransferase
Pathways
Biological processes and signaling networks where the AS3MT gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AS3MT gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- arsonoacetate metabolic process
- toxin metabolic process
- methylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- arsenite methyltransferase activity