RPTN Gene Summary [Human]
Predicted to enable calcium ion binding activity and transition metal ion binding activity. Predicted to be located in cytosol. Predicted to be active in cornified envelope. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RPTN |
| Official Name | repetin [Source:HGNC Symbol;Acc:HGNC:26809] |
| Ensembl ID | ENSG00000215853 |
| Bio databases IDs | |
| Aliases | repetin |
| Synonyms | FLJ39117, repetin |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPTN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S-100/ICaBP type calcium binding domain
- High molecular weight glutenin subunit
- EF-hand domain pair
- EFh
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- granules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPTN gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- cytosol
- extracellular region
Molecular Function
What the gene product does at the molecular level
- transition metal ion binding
- calcium ion binding