FTX Gene Summary [Human]
This gene is located upstream of XIST, within the X-inactivation center (XIC). It produces a spliced long non-coding RNA that is thought to positively regulate the expression of XIST, which is essential for the initiation and spread of X-inactivation. [provided by RefSeq, May 2015]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | FTX |
| Official Name | FTX transcript, XIST regulator [Source:HGNC Symbol;Acc:HGNC:37190] |
| Ensembl ID | ENSG00000230590 |
| Bio databases IDs | |
| Aliases | FTX transcript, XIST regulator, five prime to XIST |
| Synonyms | B230206F22Rik, BB219131, FTX transcript, XIST regulator, Ftx transcript, Xist regulator, non-protein coding, LINC00182, MIR374AHG, NCRNA00182, RGD1564124, Thcytx |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- mir-22 (includes others)
disease
- organismal death
- colorectal cancer
- placenta accreta spectrum
- renal cell carcinoma
- renal cell cancer
- glioma
- glioma formation
role in cell
- expression in
- growth
- cell viability
- proliferation
- phosphorylation in
- migration
- invasion
- invasion by
- Gap 0-Gap 1 phase
- colony formation by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FTX gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of gene expression