SETSIP Gene Summary [Human]
Enables chromatin binding activity. Involved in endothelial cell differentiation and positive regulation of transcription by RNA polymerase II. Located in cytoplasm; lipid droplet; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SETSIP |
| Official Name | SET like protein [Source:HGNC Symbol;Acc:HGNC:42937] |
| Ensembl ID | ENSG00000230667 |
| Bio databases IDs | |
| Aliases | SET like protein, SET similar protein |
| Synonyms | Ab1-115, Set, SET like protein, SETP18 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SETSIP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleosome assembly protein (NAP)
- PTZ00007
- chromatin binding
- protein binding
Pathways
Biological processes and signaling networks where the SETSIP gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- cellular membrane
- Nucleus
- Endoplasmic Reticulum
- lipid droplets
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SETSIP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endothelial cell differentiation
- positive regulation of transcription from RNA polymerase II promoter
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- lipid particle
- nucleus
- cytoplasm
- chromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone binding
- chromatin binding