MEIOSIN Gene Summary [Human]
Predicted to enable DNA binding activity and protein dimerization activity. Predicted to be involved in several processes, including activation of meiosis; cellular response to retinoic acid; and gamete generation. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MEIOSIN |
| Official Name | meiosis initiator [Source:HGNC Symbol;Acc:HGNC:44318] |
| Ensembl ID | ENSG00000237452 |
| Bio databases IDs | |
| Aliases | meiosis initiator, HMG domain containing |
| Synonyms | 9330180I18, BHMG1, EG243866, Gm4969, HMGDC, LOC676617, meiosis initiator |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MEIOSIN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- high mobility group (HMG)-box domain superfamily
- HMG (high mobility group) box
- high mobility group
- basic Helix Loop Helix (bHLH) domain superfamily
- helix loop helix domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MEIOSIN gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic cell cycle
- cellular response to retinoic acid
- oogenesis
- spermatogenesis
- activation of meiosis
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein dimerization activity