COX19 Gene Summary [Human]
COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | COX19 |
| Official Name | cytochrome c oxidase assembly factor COX19 [Source:HGNC Symbol;Acc:HGNC:28074] |
| Ensembl ID | ENSG00000240230 |
| Bio databases IDs | |
| Aliases | cytochrome c oxidase assembly factor COX19 |
| Synonyms | 1810074D02Rik, 2810437L13Rik, cytochrome c oxidase assembly factor COX19, cytochrome c oxidase assembly protein 19, RGD1305631 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human COX19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CXC motif
- CHCH domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial intermembrane space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human COX19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex IV assembly
- cellular copper ion homeostasis
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding