Cox19 Gene Summary [Mouse]

Predicted to be involved in intracellular copper ion homeostasis and mitochondrial cytochrome c oxidase assembly. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial intermembrane space. Is expressed in cranial ganglion; dorsal root ganglion; nasal cavity epithelium; and trunk unsegmented mesenchyme. Orthologous to human COX19 (cytochrome c oxidase assembly factor COX19). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cox19
Official Name
cytochrome c oxidase assembly protein 19 [Source:MGI Symbol;Acc:MGI:1915283]
Ensembl ID
ENSMUSG00000045438
Bio databases IDs NCBI: 68033 Ensembl: ENSMUSG00000045438
Aliases cytochrome c oxidase assembly protein 19
Synonyms 1810074D02Rik, 2810437L13Rik, cytochrome c oxidase assembly factor COX19, cytochrome c oxidase assembly protein 19, RGD1305631
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cox19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CXC motif
  • CHCH domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • bladder cancer
  • inflammatory bowel disease
  • COVID-19
  • Crohn disease
  • obesity
regulated by
regulates
  • Cu2+
role in cell
  • homeostasis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol
  • mitochondrial intermembrane space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cox19 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial respiratory chain complex IV assembly
  • cellular copper ion homeostasis

Cellular Component

Where in the cell the gene product is active
  • mitochondrial intermembrane space
  • mitochondrion
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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