PRAF2 Gene Summary [Human]

Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in endosome membrane. Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PRAF2
Official Name
PRA1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:28911]
Ensembl ID
ENSG00000243279
Bio databases IDs NCBI: 11230 Ensembl: ENSG00000243279
Aliases PRA1 domain family member 2
Synonyms DXImx39e, JM4, PRA1 domain family 2, PRA1 domain family member 2, PRA1 domain family, member 2, RGD1566287, Sfc20, Yip6a
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRAF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PRA1 family protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
regulated by
disease
  • Turner syndrome
role in cell
  • apoptosis
  • cell death
  • clonogenicity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • glutaminergic synapse
  • presynaptic regions
  • postsynaptic region
  • cellular membrane
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PRAF2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport
  • L-glutamate transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • endosome membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.