Praf2 Gene Summary [Mouse]
Predicted to be involved in protein transport. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynapse. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human PRAF2 (PRA1 domain family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Praf2 |
| Official Name | PRA1 domain family 2 [Source:MGI Symbol;Acc:MGI:1859607] |
| Ensembl ID | ENSMUSG00000031149 |
| Bio databases IDs | |
| Aliases | PRA1 domain family 2 |
| Synonyms | DXImx39e, JM4, PRA1 domain family 2, PRA1 domain family member 2, PRA1 domain family, member 2, RGD1566287, Sfc20, Yip6a |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Praf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PRA1 family protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- presynaptic regions
- postsynaptic region
- cellular membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Praf2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- L-glutamate transport
Cellular Component
Where in the cell the gene product is active
- membrane
- endosome membrane
Molecular Function
What the gene product does at the molecular level
- protein binding