TERB1 Gene Summary [Human]
Predicted to be involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Predicted to be located in chromosome, telomeric region and nuclear inner membrane. Predicted to colocalize with shelterin complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TERB1 |
| Official Name | telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675] |
| Ensembl ID | ENSG00000249961 |
| Bio databases IDs | |
| Aliases | telomere repeat binding bouquet formation protein 1 |
| Synonyms | 4930532D21Rik, CCDC79, RGD1310400, SPGF60, telomere repeat binding bouquet formation protein 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TERB1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SANT
- SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
- Myb-like DNA-binding domain
- peptidase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- inner nuclear membrane
- nuclear envelope
- telomeres
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TERB1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic telomere clustering
- attachment of telomeric heterochromatin to nuclear envelope
- synapsis
Cellular Component
Where in the cell the gene product is active
- chromosome, telomeric region
- nuclear inner membrane
- telosome
Molecular Function
What the gene product does at the molecular level
- protein binding