RFPL4B Gene Summary [Human]

Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RFPL4B
Official Name
ret finger protein like 4B [Source:HGNC Symbol;Acc:HGNC:33264]
Ensembl ID
ENSG00000251258
Bio databases IDs NCBI: 442247 Ensembl: ENSG00000251258
Aliases ret finger protein like 4B
Synonyms Gm3037, Gm62, ret finger protein-like 4B, RNF211
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RFPL4B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SPRY domain
  • RING-type zinc-finger
  • zinc finger of C3HC4-type, RING
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • Ring finger domain
  • associated with SPRY domains
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • facioscapulohumeral muscular dystrophy type 2
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RFPL4B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of gene expression
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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