LRIF1 Gene Summary [Human]
Predicted to enable retinoic acid receptor binding activity. Involved in dosage compensation by inactivation of X chromosome. Located in Barr body; centriolar satellite; and nucleoplasm. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LRIF1 |
| Official Name | ligand dependent nuclear receptor interacting factor 1 [Source:HGNC Symbol;Acc:HGNC:30299] |
| Ensembl ID | ENSG00000121931 |
| Bio databases IDs | |
| Aliases | ligand dependent nuclear receptor interacting factor 1, receptor interacting factor 1 |
| Synonyms | 2010012G17Rik, 4933421E11Rik, BAIP3, C1orf103, FSHD3, HBiX1, ligand dependent nuclear receptor interacting factor 1, LOC105378902, RGD1306520, RIF1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRIF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ligand-dependent nuclear receptor-interacting factor 1
- Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- nucleoplasm
- Barr body
- telomeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LRIF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- dosage compensation by inactivation of X chromosome
Cellular Component
Where in the cell the gene product is active
- Barr body
- chromosome, telomeric region
- centriolar satellite
- nuclear matrix
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- retinoic acid receptor binding