LONRF3 Gene Summary [Human]
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Multiple alternatively spliced transcript variants have been suggested, but their full length natures are not clear. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | LONRF3 |
| Official Name | LON peptidase N-terminal domain and ring finger 3 [Source:HGNC Symbol;Acc:HGNC:21152] |
| Ensembl ID | ENSG00000175556 |
| Bio databases IDs | |
| Aliases | LON peptidase N-terminal domain and ring finger 3 |
| Synonyms | 4932412G04Rik, 5730439E01RIK, A830039N02RIK, LON peptidase N-terminal domain and ring finger 3, RGD1565451, RNF127 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LONRF3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- ATP-dependent protease La (LON) substrate-binding domain
- RING-type zinc-finger
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Modified RING finger domain
- zinc finger of C3HC4-type, RING
- Ring finger
- Ring finger domain
- protein binding
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LONRF3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding