TRIM6-TRIM34 Gene Summary [Human]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene represents a readthrough transcript from genes TRIM6 and TRIM34, and it was described as a splice variant of TRIM34. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. [provided by RefSeq, Nov 2009]

Details

Type
Protein Coding
Official Symbol
TRIM6-TRIM34
Official Name
TRIM6-TRIM34 readthrough [Source:HGNC Symbol;Acc:HGNC:33440]
Ensembl ID
ENSG00000258588
Bio databases IDs NCBI: 445372 Ensembl: ENSG00000258588
Aliases TRIM6-TRIM34 readthrough
Synonyms IFP1, RNF21, RNF89, TRIM34, TRIM6, TRIM6-TRIM34 readthrough
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRIM6-TRIM34 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • B-box-type zinc finger superfamily
  • RING-type zinc-finger
  • SPRY domain
  • zinc finger of C3HC4-type, RING
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • B-box zinc finger
  • Ring finger domain
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • acute myeloid leukemia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

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