Slc25a42 Gene Summary [Mouse]
Predicted to enable ADP phosphatase activity; nucleobase-containing compound transmembrane transporter activity; and secondary active transmembrane transporter activity. Predicted to be involved in coenzyme A biosynthetic process and nucleobase-containing compound transport. Located in mitochondrial inner membrane. Orthologous to human SLC25A42 (solute carrier family 25 member 42). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc25a42 |
| Official Name | solute carrier family 25, member 42 [Source:MGI Symbol;Acc:MGI:1920345] |
| Ensembl ID | ENSMUSG00000002346 |
| Bio databases IDs | |
| Aliases | solute carrier family 25, member 42 |
| Synonyms | 2900084M01Rik, LOC684597, MECREN, MGC26694, solute carrier family 25 member 42, solute carrier family 25, member 42 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc25a42 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- purine ribonucleotide transporter
- ADP transporter
- organic cation transporter
- ATP transporter
- adenine nucleotide transporter
- apyrase
- porter
- Mitochondrial carrier protein
- coenzyme A transporter
- protein binding
- organic anion transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hereditary disorder
- recurrent metabolic crises with variable encephalomyopathic features and neurologic regression
- mitochondrial myopathy
regulates
- adenosine triphosphate
- ADP
- D-pantothenic acid
- coenzyme A
role in cell
- proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc25a42 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- AMP transport
- pantothenate metabolic process
- coenzyme A transmembrane transport
- ATP transport
- ADP transport
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- adenosine-diphosphatase activity
- AMP transmembrane transporter activity
- coenzyme A transmembrane transporter activity
- ADP transmembrane transporter activity
- ATP transmembrane transporter activity