Tmem143 Gene Summary [Mouse]
Acts upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. Orthologous to human TMEM143 (transmembrane protein 143). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem143 |
| Official Name | transmembrane protein 143 [Source:MGI Symbol;Acc:MGI:1917459] |
| Ensembl ID | ENSMUSG00000002781 |
| Bio databases IDs | |
| Aliases | transmembrane protein 143 |
| Synonyms | 2310076O21Rik, RGD1305013, transmembrane protein 143 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem143 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF3754)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem143 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding