Mtfp1 Gene Summary [Mouse]
Acts upstream of or within apoptotic process and mitochondrion organization. Located in mitochondrion. Is expressed in pancreas epithelium. Orthologous to human MTFP1 (mitochondrial fission process 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtfp1 |
| Official Name | mitochondrial fission process 1 [Source:MGI Symbol;Acc:MGI:1916686] |
| Ensembl ID | ENSMUSG00000004748 |
| Bio databases IDs | |
| Aliases | mitochondrial fission process 1 |
| Synonyms | 1700020C11Rik, 2610507A21Rik, HSPC242, mitochondrial fission process 1, MTP18 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mtfp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitochondrial 18 KDa protein (MTP18)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- impaired glucose tolerance
- hepatic steatosis
- dilated cardiomyopathy
regulates
role in cell
- apoptosis
- organization
- morphology
- oxidative phosphorylation in
- opening in
- opening
- mitochondrial respiration in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mitochondrial fraction
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mtfp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- mitochondrial fission
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding