Uqcc1 Gene Summary [Mouse]
Predicted to be involved in mitochondrial respiratory chain complex III assembly. Located in cytoplasmic vesicle. Is expressed in several structures, including eye and nervous system. Orthologous to human UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Uqcc1 |
| Official Name | ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:MGI Symbol;Acc:MGI:1929472] |
| Ensembl ID | ENSMUSG00000005882 |
| Bio databases IDs | |
| Aliases | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| Synonyms | 2310079L17Rik, 2410003P15Rik, 3110038N19Rik, BFZB, Bfzp, C20orf44, CBP3, ubiquinol-cytochrome c reductase complex assembly factor 1, UQCC |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uqcc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquinol-cytochrome C chaperone
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- osteoarthritis
- diffuse idiopathic skeletal hyperostosis
- non-melanoma skin cancer
- flatfoot
- congenital dislocation of hip
regulates
- Cytochrome bc1
role in cell
- assembly in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Uqcc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex III assembly
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytoplasmic vesicle
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding