Gatad1 Gene Summary [Mouse]

Predicted to enable sequence-specific DNA binding activity and zinc ion binding activity. Predicted to be involved in chromatin organization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including eye; gonad; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2B. Orthologous to human GATAD1 (GATA zinc finger domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gatad1
Official Name
GATA zinc finger domain containing 1 [Source:MGI Symbol;Acc:MGI:1914460]
Ensembl ID
ENSMUSG00000007415
Bio databases IDs NCBI: 67210 Ensembl: ENSMUSG00000007415
Aliases GATA zinc finger domain containing 1
Synonyms 2310031E19Rik, 2810047M21Rik, 8430439A17RIK, 9130430G15Rik, B330017N08RIK, CMD2B, GATA zinc finger domain containing 1, ODAG, RG083M05.2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gatad1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dilated cardiomyopathy
  • dilated cardiomyopathy type 2B
regulated by
  • lipopolysaccharide
  • topotecan
role in cell
  • cell viability
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gatad1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • chromatin organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • sequence-specific DNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.