Carhsp1 Gene Summary [Mouse]
Predicted to enable mRNA 3'-UTR binding activity. Involved in regulation of mRNA stability. Located in P granule and cytosol. Part of cytoplasmic exosome (RNase complex). Is expressed in dorsal root ganglion; genitourinary system; limb; neural tube; and telencephalon. Orthologous to human CARHSP1 (calcium regulated heat stable protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Carhsp1 |
| Official Name | calcium regulated heat stable protein 1 [Source:MGI Symbol;Acc:MGI:1196368] |
| Ensembl ID | ENSMUSG00000008393 |
| Bio databases IDs | |
| Aliases | calcium regulated heat stable protein 1 |
| Synonyms | 1200011K09Rik, calcium regulated heat stable protein 1, CRHSP-24, CSDC1, D16Ertd465e |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Carhsp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S1_like
- transcription regulator
- mRNA 3' UTR binding
- protein binding
- Cold shock protein domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cerebral aneurysm
regulated by
- tetradecanoylphorbol acetate
- calyculin A
- fostriecin
- propylthiouracil
- okadaic acid
- OVALBUMIN
- IgE
- TP53
- sirolimus
- lipopolysaccharide
role in cell
- expression in
- radiosensitivity
- signal transduction in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic ribonucleoprotein granule
- Nucleus
- cytosol
- basal cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Carhsp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of mRNA stability
- intracellular signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasmic exosome (RNase complex)
- cytoplasm
- P granule
- cytoplasmic mRNA processing body
- cytosol
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- protein binding
- mRNA 3'-UTR binding