Tmem115 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in Golgi cisterna membrane and nucleus. Predicted to be part of Golgi transport complex. Predicted to be active in Golgi apparatus. Orthologous to human TMEM115 (transmembrane protein 115). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem115 |
| Official Name | transmembrane protein 115 [Source:MGI Symbol;Acc:MGI:1930765] |
| Ensembl ID | ENSMUSG00000010045 |
| Bio databases IDs | |
| Aliases | transmembrane protein 115 |
| Synonyms | LOC100910557, PL6, Pp6, RGD1310540, transmembrane protein 115 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem115 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- identical protein binding
- Rhomboid family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Nucleus
- Golgi Apparatus
- Golgi membrane
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem115 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retrograde vesicle-mediated transport, Golgi to ER
- negative regulation of cell proliferation
- protein transport
Cellular Component
Where in the cell the gene product is active
- nucleus
- Golgi transport complex
- Golgi cisterna membrane
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding