Aspg Gene Summary [Mouse]
Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups; asparaginase activity; and carboxylic ester hydrolase activity. Predicted to be involved in asparagine metabolic process and phospholipid metabolic process. Orthologous to human ASPG (asparaginase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Aspg |
| Official Name | asparaginase [Source:MGI Symbol;Acc:MGI:2144822] |
| Ensembl ID | ENSMUSG00000037686 |
| Bio databases IDs | |
| Aliases | asparaginase |
| Synonyms | A530050D06Rik, asparaginase, C14orf76, Gm690, GPA/WT, hASNase1, LOC246266, LYSOLP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Aspg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- Bacterial L-asparaginases and related enzymes
- lysophospholipase
- asparaginase
- Ankyrin repeats (3 copies)
- enzyme
- protein binding
- Ankyrin repeat
- 1-alkyl-2-acetylglycerophosphocholine esterase
- Glutaminase/Asparaginase C-terminal domain
- glutamyl-tRNA(Gln) amidotransferase, subunit D
- Non-amino-acyl group acyltransferase
- Asparaginase, N-terminal
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Aspg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- aspartate family amino acid metabolic process
- lipid catabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- lysophospholipase activity
- transferase activity, transferring acyl groups other than amino-acyl groups
- protein binding
- 1-alkyl-2-acetylglycerophosphocholine esterase activity
- asparaginase activity