Cfap161 Gene Summary [Mouse]
Involved in flagellated sperm motility. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; genitourinary system; lung; node; and sensory organ. Orthologous to human CFAP161 (cilia and flagella associated protein 161). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfap161 |
| Official Name | cilia and flagella associated protein 161 [Source:MGI Symbol;Acc:MGI:1922806] |
| Ensembl ID | ENSMUSG00000011154 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 161 |
| Synonyms | 1700026D08Rik, C15orf26, cilia and flagella associated protein 161, RGD1310371 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap161 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- axonemes
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap161 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
Cellular Component
Where in the cell the gene product is active
- motile cilium
- axonemal microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding