Enkd1 Gene Summary [Mouse]
Predicted to enable alpha-tubulin binding activity and microtubule binding activity. Involved in motile cilium assembly and non-motile cilium assembly. Located in 9+0 non-motile cilium; ciliary base; and microtubule organizing center. Is expressed in several structures, including adrenal gland; brain ventricular layer; ileum; male reproductive gland or organ; and sensory organ. Orthologous to human ENKD1 (enkurin domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Enkd1 |
| Official Name | enkurin domain containing 1 [Source:MGI Symbol;Acc:MGI:2142593] |
| Ensembl ID | ENSMUSG00000013155 |
| Bio databases IDs | |
| Aliases | enkurin domain containing 1 |
| Synonyms | C16orf48, DAKV6410, Dkfzp434a1319, E130303B06Rik, enkurin domain containing 1, FBB11, RGD1307357 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Enkd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Calmodulin-binding
- alpha-tubulin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- non-motile cilium
- cilia
- Plasma Membrane
- basal bodies
- centrosome
- centriole
- cytoplasmic microtubule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Enkd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- establishment of mitotic spindle orientation
- motile cilium assembly
Cellular Component
Where in the cell the gene product is active
- centrosome
- microtubule cytoskeleton
- cilium basal body
- centriole
- spindle pole
- cytoplasmic microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- alpha-tubulin binding
- microtubule binding