Ints2 Gene Summary [Mouse]

Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of integrator complex. Orthologous to human INTS2 (integrator complex subunit 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ints2
Official Name
integrator complex subunit 2 [Source:MGI Symbol;Acc:MGI:1917672]
Ensembl ID
ENSMUSG00000018068
Bio databases IDs NCBI: 70422 Ensembl: ENSMUSG00000018068
Aliases integrator complex subunit 2
Synonyms 2810417D08Rik, INT2, integrator complex subunit 2, KIAA1287, mKIAA1287, RGD1305547
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ints2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Integrator complex subunit 2
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ints2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • snRNA processing
  • regulation of transcription elongation from RNA polymerase II promoter
  • snRNA 3'-end processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear membrane
  • cytoplasm
  • membrane
  • nucleoplasm
  • integrator complex

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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