Tlcd1 Gene Summary [Mouse]
Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be active in plasma membrane. Orthologous to human TLCD1 (TLC domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tlcd1 |
| Official Name | TLC domain containing 1 [Source:MGI Symbol;Acc:MGI:1915572] |
| Ensembl ID | ENSMUSG00000019437 |
| Bio databases IDs | |
| Aliases | TLC domain containing 1 |
| Synonyms | TLC domain containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tlcd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TLC domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- 18:1/18:2 phosphatidylethanolamine
- 18:1/22:6 phosphatidylethanolamine
- 16:1(9Z)/16:1(9Z) phosphatidylethanolamine
- 16:1/18:2 phosphatidylethanolamine
- phospholipid
- 16:1/20:4 phosphatidylethanolamine
- 18:1/20:4 phosphatidylethanolamine
regulated by
- histamine
- TP73
- RHO
- PF-3893787
disease
- diet-induced nonalcoholic steatohepatitis
role in cell
- assembly
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tlcd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- plasma membrane organization
- regulation of membrane lipid distribution
- membrane assembly
- phospholipid homeostasis
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding