Slc6a15 Gene Summary [Mouse]
Enables branched-chain amino acid:sodium symporter activity; neutral L-amino acid:sodium symporter activity; and proline:sodium symporter activity. Involved in L-leucine transport and proline transport. Located in membrane. Is expressed in alimentary system; central nervous system; dorsal root ganglion; metanephros; and sensory organ. Orthologous to human SLC6A15 (solute carrier family 6 member 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Slc6a15 |
| Official Name | solute carrier family 6 (neurotransmitter transporter), member 15 [Source:MGI Symbol;Acc:MGI:2143484] |
| Ensembl ID | ENSMUSG00000019894 |
| Bio databases IDs | |
| Aliases | solute carrier family 6 (neurotransmitter transporter), member 15 |
| Synonyms | 6430590A10RIK, AA536730, hv7-3, NTT73, SBAT1, solute carrier family 6 member 15, solute carrier family 6 (neurotransmitter transporter), member 15, V7-3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc6a15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- neutral amino acid:sodium symporter
- branched-chain amino acid:sodium symporter
- Sodium:neurotransmitter symporter family
- protein binding
- Solute carrier families 5 and 6-like; solute binding domain
- proline:sodium symporter
- amino acid transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- perikaryon
- axons
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc6a15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neurotransmitter transport
- neutral amino acid transport
- sodium ion transmembrane transport
- proline transport
- amino acid transport
- amino acid transmembrane transport
- leucine transport
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- neurotransmitter transporter activity
- protein binding
- neutral amino acid:sodium symporter activity
- amino acid transmembrane transporter activity
- proline:sodium symporter activity
- branched-chain amino acid:sodium symporter activity