Fxyd3 Gene Summary [Mouse]
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The encoded protein is a transmembrane protein that functions as a specific regulator of Na,K-ATPase. [provided by RefSeq, Aug 2009]
Details
| Type | Protein Coding |
| Official Symbol | Fxyd3 |
| Official Name | FXYD domain-containing ion transport regulator 3 [Source:MGI Symbol;Acc:MGI:107497] |
| Ensembl ID | ENSMUSG00000057092 |
| Bio databases IDs | |
| Aliases | FXYD domain-containing ion transport regulator 3 |
| Synonyms | FXYD domain-containing ion transport regulator 3, ION TRANSPORT REGULATOR p11, MAT8, PLML |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fxyd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATPase binding
- ATP1G1/PLM/MAT8 family
- chloride channel
- protein binding
- phenylalanine-X-tyrosine-aspartate (FXYD) family
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fxyd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- sodium ion transport
- regulation of sodium ion transmembrane transporter activity
- regulation of ion transport
- chloride transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- sodium channel regulator activity
- chloride channel activity
- ATPase binding