Rmnd1 Gene Summary [Mouse]

Predicted to be involved in positive regulation of mitochondrial translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 11. Orthologous to human RMND1 (required for meiotic nuclear division 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rmnd1
Official Name
required for meiotic nuclear division 1 homolog [Source:MGI Symbol;Acc:MGI:1913334]
Ensembl ID
ENSMUSG00000019763
Bio databases IDs NCBI: 66084 Ensembl: ENSMUSG00000019763
Aliases required for meiotic nuclear division 1 homolog
Synonyms 0610042C05Rik, bA351K16, bA351K16.3, C6orf96, COXPD11, Iag-1, required for meiotic nuclear division 1 homolog, RGD1309546, RMD1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rmnd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • RMND1/Sif2-Sif3/Mrx10, DUF155

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • mitochondrial disorder
  • combined oxidative phosphorylation deficiency 11
  • nephronophthisis
  • hereditary disorder
  • breast carcinoma
  • oxidative phosphorylation disease
regulated by
  • beta-estradiol
  • progestin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rmnd1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of mitochondrial translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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