Mrps23 Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; genitourinary system; heart; and liver. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 46. Orthologous to human MRPS23 (mitochondrial ribosomal protein S23). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrps23 |
| Official Name | mitochondrial ribosomal protein S23 [Source:MGI Symbol;Acc:MGI:1928138] |
| Ensembl ID | ENSMUSG00000023723 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein S23 |
| Synonyms | CGI-138, COXPD46, D11Bwg1153e, HSPC329, mitochondrial ribosomal protein S23, mS23, Rpms23, S23mt |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrps23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Mitochondrial ribosomal protein S23
- Arabidopsis thaliana At1g26750 and similar proteins
- protein binding
Pathways
Biological processes and signaling networks where the Mrps23 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal adenoma
- colorectal adenoma formation
- insulin resistance
- luminal breast cancer
- combined oxidative phosphorylation deficiency 46
- leiomyoma
- leiomyomatosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrps23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- mitochondrion
- mitochondrial small ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome