Mfap3 Gene Summary [Mouse]
Predicted to be located in plasma membrane. Is expressed in genitourinary system and heart ventricle. Orthologous to human MFAP3 (microfibril associated protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfap3 |
| Official Name | microfibrillar-associated protein 3 [Source:MGI Symbol;Acc:MGI:1924068] |
| Ensembl ID | ENSMUSG00000020522 |
| Bio databases IDs | |
| Aliases | microfibrillar-associated protein 3 |
| Synonyms | 2610509F16RIK, 2700079M14RIK, microfibril associated protein 3, microfibrillar-associated protein 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfap3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfap3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of ERK1 and ERK2 cascade
- interleukin-15-mediated signaling pathway
- T cell activation
Cellular Component
Where in the cell the gene product is active
- membrane raft
- external side of plasma membrane
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- MHC class II protein binding