Tmem94 Gene Summary [Mouse]
Enables P-type magnesium transporter activity. Involved in intracellular magnesium ion homeostasis and magnesium ion transport from cytosol to endoplasmic reticulum. Acts upstream of or within embryonic brain development and embryonic heart tube development. Is active in endoplasmic reticulum membrane. Is expressed in central nervous system; dorsal root ganglion; liver; and retina. Orthologous to human TMEM94 (transmembrane protein 94). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem94 |
| Official Name | transmembrane protein 94 [Source:MGI Symbol;Acc:MGI:1919197] |
| Ensembl ID | ENSMUSG00000020747 |
| Bio databases IDs | |
| Aliases | transmembrane protein 94 |
| Synonyms | 2310067B10Rik, ERMA, IDDCDF, KIAA0195, mKIAA0195, transmembrane protein 94 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem94 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mg2+-importing ATPase
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- endoplasmic reticulum membrane
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem94 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular magnesium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- magnesium-importing ATPase activity