Slc17a2 Gene Summary [Mouse]

Enables urate transmembrane transporter activity. Predicted to be involved in sodium ion transport; transmembrane transport; and urate transport. Located in apical plasma membrane. Orthologous to human SLC17A2 (solute carrier family 17 member 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Slc17a2
Official Name
solute carrier family 17 (sodium phosphate), member 2 [Source:MGI Symbol;Acc:MGI:2443098]
Ensembl ID
ENSMUSG00000036110
Bio databases IDs NCBI: 218103 Ensembl: ENSMUSG00000036110
Aliases solute carrier family 17 (sodium phosphate), member 2
Synonyms C730032N17RIK, NPT3, solute carrier family 17 member 2, solute carrier family 17, member 2, solute carrier family 17 (sodium phosphate), member 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc17a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phosphoglycerate transporter family protein
  • benzoate transport
  • Sugar (and other) transporter
  • Major Facilitator Superfamily
  • Multidrug resistance protein
  • Na(+)-dependent inorganic phosphate cotransporter
  • sodium:phosphate symporter
  • urate transporter
  • transporter

Pathways

Biological processes and signaling networks where the Slc17a2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • polycythemia vera
  • gastric carcinoma
  • gastric epithelial cancer
  • systemic lupus erythematosus
regulated by
regulates
  • phosphate
  • Na+

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • apical membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc17a2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sodium ion transport
  • sodium ion transmembrane transport
  • urate transport
  • anion transport
  • phosphate-containing compound metabolic process

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane
  • apical plasma membrane

Molecular Function

What the gene product does at the molecular level
  • sodium:phosphate symporter activity
  • transmembrane transporter activity
  • urate transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.