Krt36 Gene Summary [Mouse]
A structural constituent of skin epidermis. Involved in regulation of keratinocyte differentiation. Located in intermediate filament cytoskeleton. Is expressed in several structures, including cranium; fronto-nasal process; skin; surface ectoderm; and tongue. Orthologous to human KRT36 (keratin 36). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt36 |
| Official Name | keratin 36 [Source:MGI Symbol;Acc:MGI:109364] |
| Ensembl ID | ENSMUSG00000020916 |
| Bio databases IDs | |
| Aliases | keratin 36 |
| Synonyms | HA6, hHa6, HRa-1, K36, Ka31, keratin 36, Keratin complex 1, acidic, gene 5, Krt1-22, Krt1-5, KRTHA6, MHRa-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt36 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of epidermis
- protein binding
- Intermediate filament protein
- Spc7 kinetochore protein
Pathways
Biological processes and signaling networks where the Krt36 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filament cytoskeleton
- cytosol
- keratin intermediate filaments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Krt36 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell differentiation
- regulation of keratinocyte differentiation
- intermediate filament organization
Cellular Component
Where in the cell the gene product is active
- keratin filament
- extracellular vesicular exosome
- intermediate filament cytoskeleton
- cytosol
Molecular Function
What the gene product does at the molecular level
- structural constituent of epidermis