Wdr37 Gene Summary [Mouse]
Involved in lymphocyte homeostasis. Acts upstream of or within corpus callosum development. Predicted to be located in cytoplasm and nucleus. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in neurooculocardiogenitourinary syndrome. Orthologous to human WDR37 (WD repeat domain 37). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr37 |
| Official Name | WD repeat domain 37 [Source:MGI Symbol;Acc:MGI:1920393] |
| Ensembl ID | ENSMUSG00000021147 |
| Bio databases IDs | |
| Aliases | WD repeat domain 37 |
| Synonyms | 3110035P10RIK, 4933417A01Rik, NOCGUS, WD repeat domain 37 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr37 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr37 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lymphocyte homeostasis
- corpus callosum development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding