Cetn3 Gene Summary [Mouse]
Enables G-protein beta/gamma-subunit complex binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization. Located in centriole; ciliary basal body; and photoreceptor connecting cilium. Is expressed in several structures, including foregut; musculoskeletal system; nervous system; sensory organ; and submandibular gland primordium. Orthologous to human CETN3 (centrin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cetn3 |
| Official Name | centrin 3 [Source:MGI Symbol;Acc:MGI:1097706] |
| Ensembl ID | ENSMUSG00000021537 |
| Bio databases IDs | |
| Aliases | centrin 3 |
| Synonyms | CDC31, CEN3, centrin 3, LOC100912538, MmCEN3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cetn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- EF-hand, calcium binding motif
- EF-hand domain
- binding protein
- EF-hand domain pair
- EF hand
- EFh
- protein binding
- EFh_MICU
- EFh_PI-PLC
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary transition zone
- basal bodies
- centrosome
- centriole
- connecting cilia
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cetn3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- centrosome cycle
- protein transport
- microtubule cytoskeleton organization
- mRNA transport
Cellular Component
Where in the cell the gene product is active
- photoreceptor connecting cilium
- centrosome
- microtubule organizing center
- cytoplasm
- centriole
- cilium basal body
- nucleolus
- transcription export complex 2
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- G-protein beta/gamma-subunit complex binding
- microtubule binding