Dusp13 Gene Summary [Mouse]
Enables protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation and negative regulation of MAPK cascade. Predicted to be active in cytoplasm. Is expressed in ductus deferens; epididymis; ileum; and testis. Orthologous to human DUSP13B (dual specificity phosphatase 13B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dusp13 |
| Official Name | dual specificity phosphatase 13 [Source:MGI Symbol;Acc:MGI:1351599] |
| Ensembl ID | ENSMUSG00000021768 |
| Bio databases IDs | |
| Aliases | dual specificity phosphatase 13 |
| Synonyms | dual specificity phosphatase 13B, DUSP13, DUSP13A, Gm1203, LMW-DSP6, LOC108348179, MDSP, SKRP4, TMDP, TS-DSP6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dusp13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dual specificity phosphatase, catalytic domain
- protein tyrosine/serine/threonine phosphatase
- phosphoprotein phosphatase
- phosphatase
- protein binding
- PTP_DSP_cys
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dusp13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic cell cycle
- negative regulation of MAPK cascade
- spermatogenesis
- protein dephosphorylation
- dephosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- MAP kinase phosphatase activity
- protein tyrosine phosphatase activity
- phosphatase activity
- myosin phosphatase activity
- protein tyrosine/serine/threonine phosphatase activity