Anxa8 Gene Summary [Mouse]
Predicted to enable several functions, including actin filament binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipid binding activity. Predicted to be involved in endosomal transport and endosome organization. Predicted to be located in cytosol; late endosome membrane; and plasma membrane. Predicted to be active in cytoplasm; sarcolemma; and vesicle membrane. Is expressed in several structures, including genitourinary system; gut; respiratory system; sensory organ; and skin. Orthologous to human ANXA8 (annexin A8) and ANXA8L1 (annexin A8 like 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Anxa8 |
| Official Name | annexin A8 [Source:MGI Symbol;Acc:MGI:1201374] |
| Ensembl ID | ENSMUSG00000021950 |
| Bio databases IDs | |
| Aliases | annexin A8 |
| Synonyms | annexin A8, Annexin viii, Anx8, Anxa6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Anxa8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- binding protein
- phosphatidylinositol-3,4,5-triphosphate binding
- phosphatidylinositol-4,5-bisphosphate binding
- calcium ion binding
- calcium-dependent phospholipid binding
- Annexin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
- endosomal membrane